Hydroxypinacolone Retinoate (HPR) 10% | Advanced Vitamin A Ester

Hydroxypinacolone Retinoate (HPR) 10% is a next-generation retinoid ester that delivers visible skin-renewing benefits with minimal irritation. Pre-dispersed in Isosorbide Dimethyl Ether (IDE), this advanced active provides direct retinoic-acid activity without the metabolic conversion required by standard retinols — offering maximum effectiveness with exceptional skin tolerance.

This 10 % pre-blend (1 part HPR : 9 parts carrier) ensures stability, potency, and ease of formulation. Perfect for serums, facial oils, and overnight treatments targeting fine lines, uneven texture, and loss of firmness.

Key Benefits

• Promotes smoother, more even skin tone and texture
• Targets signs of aging without redness or flaking
• Delivers stable, bioavailable Vitamin A performance
• Suitable for sensitive and mature skin types
• Ideal for restorative night-time skincare formulations

Formulation Guidelines

• Usage Rate: 0.5 – 2 % of total formula
• Phase: Add during cool-down (< 40 °C / 104 °F)
• Solubility: Oil-soluble
• Recommended pH: 4.5 – 6.5
• Combine With: Squalane, Bakuchiol, Bisabolol, or Ceramide Complex for soothing synergy
• Storage: Keep cool (50°–77 °F / 10°–25 °C), away from air and light to preserve potency

Suggested Applications

• Night serums and facial oils
• Anti-aging treatments targeting fine lines and discoloration
• Brightening or resurfacing formulas for dry or mature skin
• Gentle retinoid options for sensitive skin care lines

INCI & Technical Details

INCI: Hydroxypinacolone Retinoate (and) Isosorbide Dimethyl Ether
Concentration: 10 % HPR prediluted in 90 % IDE
Solubility: Oil-soluble
Appearance: Golden-amber liquid
Shelf Life: 24 months (sealed, cool, dark storage)
Grade: Cosmetic / External Use Only

Natural Living Note

A balanced approach to Vitamin A — powerful yet gentle. HPR exemplifies the NSI philosophy of effective formulation without compromise, bridging science-backed actives with mindful skin health. Perfect for natural formulators seeking modern anti-aging performance within clean beauty guidelines.